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It reflects a deeper transformation in how we understand obesity, how we define disease, and how pharmacology is reimagining metabolic health

Many patients eventually reduce their dose, switch to maintenance-level dosing, or transition off the medication entirely

PLoS Pathog 7:e1001335 Harada A, Yoneyama S, Doi SC, Aoyama M (2003) Changes in contents of free amino acids and soluble carbohydrates during fruit-body development of Hypsizygus marmoreus

Funding NIHs National Institute on Drug Abuse (NIDA), National Institute on Alcohol Abuse and Alcoholism (NIAAA), National Institute on Aging (NIA), and National Cancer Institute (NCI).